Strangly Rearranged

Hello, my computer is in desperate need of surgeon , seriously though, this problem is so annoying!
First, my desktop is often rearranging itself, and some of my files are even deleted altogether, like there are gremlins running amuck inside .
Also, when I restart my computer after running any virus program that let's me know to do so (for the remaining files to be deleted,) IT JUST SHUTS DOWN COMPLETELY, NO RESTART WHATSOEVER. I cannot seem to restart my computer even to refresh a slow session, I have to do a hard reboot. I also downloaded Malwarebytes Antimalware, at the first their was an error message stating that one of the files could not be executed, I got in touch with them, and they had me change on of their file names, I finally have had some success with downloading their program, even then, the darn thing kept being deleted from my computer, this has happened several times after the download, now, their program has stayed put, yet there are these issues with my computer even after running their program. I even have McAfee running on my system, still no luck there either... PLEASE HELP ME! (One last thing to note, when I boot to safe mode/w networking, I cannot access the internet)!!

I am sorry, I hope that this is attached to the same post, my Desktop also gives me s fragmented blue screen, I'll attach a picture of it if I can!

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